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KMID : 0361620080430020247
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Journal of the Korean Orthopaedic Association
2008 Volume.43 No. 2 p.247 ~ p.251
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Aberrant Chromosomal Alterations in Bizarre Parosteal Osteochondromatous Proliferation (Nora’s Lesion) of Hand - A Case Report -
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Kim Kap-Jung
Kim Ha-Yong
Yang Dae-Suk
Choy Won-Sik
Ihm Chun-Hwa
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Abstract
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Bizarre parosteal osteochondromatous proliferation is a disease similar to an osteochondroma that usually involves the metatarsal, metacarpal, proximal and middle phalanx. The symptoms are normally caused by the bone mass, the condition has a benign clinical course but recurrence is common. Recently, it was reported that there is a translocation between chromosome 1 and 17. We report a case of BPOP in the middle phalanx of hand with translocations and duplication in cytogenetic karyotyping with a review of relevant literature.
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KEYWORD
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Hand, Bizarre parosteal osteochondromatous proliferation, Cytogenetic karyotyping
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